Accession Number:

AD0625953

Title:

NATURAL DRUG RESISTANCE OF HETEROGENEOUS SINGLE CELL TRANSPLANTS.

Descriptive Note:

Semi-annual rept. on J-202, 17 Sep 64-16 Mar 65,

Corporate Author:

SASAKI FOUNDATION MEDICAL INSTITUTION TOKYO (JAPAN)

Personal Author(s):

• Yoshida,Tomizo

Report Date:

1965-03-16

Pagination or Media Count:

4.0

Abstract:

The present study attempts to demonstrate precisely the following points a whether cellular constitution of a clonal cancer cell population is uniform as regards the degree of natural drug resistance b whether the degree of drug resistance of cancer clone fluctuates during animal passages and c whether any correlation is found between the degree of drug resistance and chromosonal constitution of cells in a cancer clone. The drug resistance under question in this case is not acquired but natural one.

Descriptors:

• (*CANCER
• DRUGS)
• (*DRUGS
• RESISTANCE(BIOLOGY))
• TRANSPLANTATION
• CELLS(BIOLOGY)
• CHROMOSOMES
• JAPAN

Subject Categories:

• Medicine and Medical Research
• Pharmacology

Distribution Statement:

APPROVED FOR PUBLIC RELEASE