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STUDIES ON THE HEMOGLOBIN-OXYGEN EQUILIBRIUM.
Semiannual abstract rept. 18 Jun-17 Dec 64,
NARA MEDICAL COLL KASHIHARA CITY (JAPAN) DEPT OF PHYSIOLOGY
Pagination or Media Count:
Whole blood and hemolysate from a hemoglobin MO heterozygote showed a lower oxygen affinity than normal adult blood and hemolysate. A decreased heme-heme interaction was also observed in the hemolysate from the patient. Extent of hybridization between human adult and canine hemoglobins decreased with the decrease of oxygen saturation of the pigments. A rough rectangular hyperbolic relation was noticed between the extent of hybridization and the degree of oxygenation. Heterogenous feature of chromaiographic fractions of rat hemoglobin was revealed on the starch-gel electrophoretic analysis of them. A simple and efficient apparatus was developed for concentrating any dilute macromolecule solution. Author
APPROVED FOR PUBLIC RELEASE