Accession Number:

AD0625849

Title:

STUDIES ON THE HEMOGLOBIN-OXYGEN EQUILIBRIUM.

Descriptive Note:

Semiannual abstract rept. 18 Jun-17 Dec 64,

Corporate Author:

NARA MEDICAL COLL KASHIHARA CITY (JAPAN) DEPT OF PHYSIOLOGY

Personal Author(s):

Report Date:

1964-12-17

Pagination or Media Count:

18.0

Abstract:

Whole blood and hemolysate from a hemoglobin MO heterozygote showed a lower oxygen affinity than normal adult blood and hemolysate. A decreased heme-heme interaction was also observed in the hemolysate from the patient. Extent of hybridization between human adult and canine hemoglobins decreased with the decrease of oxygen saturation of the pigments. A rough rectangular hyperbolic relation was noticed between the extent of hybridization and the degree of oxygenation. Heterogenous feature of chromaiographic fractions of rat hemoglobin was revealed on the starch-gel electrophoretic analysis of them. A simple and efficient apparatus was developed for concentrating any dilute macromolecule solution. Author

Subject Categories:

  • Biochemistry
  • Anatomy and Physiology

Distribution Statement:

APPROVED FOR PUBLIC RELEASE