Accession Number:

AD0625623

Title:

BIOLOGICAL PROPERTIES OF THE NIIEG TULAREMIA VACCINE STRAINS

Descriptive Note:

Corporate Author:

ARMY BIOLOGICAL LABS FREDERICK MD

Personal Author(s):

• Sirotyuk, L. V.

Report Date:

1965-06-01

Pagination or Media Count:

7.0

Abstract:

The NIIEG vaccine tularemia strains No. 10, 33 and 53 practically preserved all their biological characteristics in the process of a 10-year storage in a dried state in saccharose-gelatin medium. The NIIEG vaccine strains No. 10 and 53 are harmless for guinea pigs and highly immunogenic in tests on white mice and guinea pigs, but possess an increased residual virulence for white mice in comparison with the standard Gayskiy No. 15 strain. The NIIEG vaccine strains No. 10 and 53, based both on their biological properties disclosed at the present time as well as in a test on their wide application in the past, may be recommended as reserves for the production of live tularemia vaccine. The NIIEG vaccine strain No. 33, based on agglutinability and immunogenic properties, is inferior to the other strains and cannot be recommended for the production of live vaccine.

Descriptors:

• *PASTEURELLA
• USSR
• PRODUCTION
• VIABILITY
• TRANSLATIONS
• STORAGE
• MICE
• IMMUNITY
• VACCINES
• GUINEA PIGS
• CULTURE MEDIA

Subject Categories:

• Microbiology

Distribution Statement:

APPROVED FOR PUBLIC RELEASE