Accession Number:

AD0625410

Title:

SPIKE PROBABILITIES IN NEURONES: INFLUENCE OF TEMPORAL STRUCTURE IN THE TRAIN OF SYNAPTIC EVENTS,

Descriptive Note:

Corporate Author:

RAND CORP SANTA MONICA CALIF

Personal Author(s):

• Segundo,Jose P.
• Perkel,Donald H.
• Moore,George P.

Report Date:

1965-12-01

Pagination or Media Count:

79.0

Abstract:

Certain input-output relations were studied by way of intraneuronal recordings in isolated visceral ganglia of Aplysia californica. All cells exhibited a prolonged sequence of excitatory postsynaptic potentials EPSPs of a single type and, as a consequence, produced recurrent spikes. EPSPs either 1 occurred spontaneously or 2 were initiated by stimulating a connective with shocks from a stimulator driven by a Geiger counter. The prespike epoch was analyzed and the events that trigger the postsynaptic spike were identified in a probabilistic manner. Experiments in digital-computer-simulated neurons reproduced and extended the results of animal experiments.

Descriptors:

• (*NERVE IMPULSES
• PROBABILITY)
• TIME
• STATISTICAL ANALYSIS
• NERVE CELLS
• BIONICS
• GANGLIA
• CYBERNETICS
• DIGITAL COMPUTERS

Subject Categories:

• Medicine and Medical Research
• Bionics

Distribution Statement:

APPROVED FOR PUBLIC RELEASE