Accession Number:

AD0623615

Title:

METABOLIC STUDIES OF ENERGY DENSE COMPOUNDS FOR AEROSPACE NUTRITION

Descriptive Note:

Final rept. for 28 Nov 1962-15 Sep 1964

Corporate Author:

MASSACHUSETTS INST OF TECH CAMBRIDGE DEPT OF NUTRITION AND FOOD SCIENCE

Personal Author(s):

• Miller, S. A.
• Dymsza, H. A.
• Tannenbaum, S. R.
• Goldblith, S. A.

Report Date:

1965-08-01

Pagination or Media Count:

54.0

Abstract:

The aim of these studies was the development of model compounds with which information useful in understanding energy metabolism might be obtained to aid in development of food for space travel. Seven-month studies feeding rats with 1,3-butanediol have been completed. The results of these studies confirm the utilization of this compound as an energy source. Measurement of a number of metabolic parameters at the completion of the study support the contention that 1,3-butanediol is probably metabolized through carbohydrate rather than fat pathways. Metabolism studies with 2,4-dimethylheptanoic acid labeled with C14 in the alpha methyl group indicate that this compound as predicted is oxidized through propionate. Design and construction details of the direct animal calorimeter are presented. Results of a limited number of studies with rats fed various diets indicate that the device fulfills its design functions.

Descriptors:

• *ASTRONAUTS
• CARBOHYDRATES
• CARBOXYLIC ACIDS
• CHROMATOGRAPHY
• DIET
• ESTERS
• FATS
• LABELED SUBSTANCES
• LIFE SUPPORT SYSTEMS
• METABOLISM
• NUTRITION
• OXIDATION
• PROPIONIC ACID
• PROTEINS
• RATS
• SPACE BIOLOGY
• TOXICITY

Subject Categories:

• Personnel Management and Labor Relations

Distribution Statement:

APPROVED FOR PUBLIC RELEASE