Accession Number:

AD0620540

Title:

THYTHMIC RESPONSE OF SERRATIA MARCESCENS TO ELEVATED TEMPERATURE,

Descriptive Note:

Corporate Author:

CALIFORNIA UNIV BERKELEY

Personal Author(s):

Report Date:

1964-11-24

Pagination or Media Count:

9.0

Abstract:

Populations of Serratia marcescens of varied ages and pretreatments, which had been grown in a chemically defined medium, were subjected to thermal stress at 50 to 56 C. The numbers of survivors were plotted vs. time to form survivor curves, and the curves were assembled to form three-dimensional models. The manner in which survivors varied as a function of age and time of heating was variable and often rhythmic. Different three-dimensional patterns were found when different inoculum for the test culture was used. Apparently some dead cells again produced colonies after extended heating periods recuperation this tendency varied with the age of the culture. Diminutive colony forms, which produced normal colonies upon transfer, appeared and disappeared during heating this tendency fluctuated with age. It is suggested that survivor curves represent a distribution of resistant forms within the population, and that this distribution varies in a manner best described in terms of servomechanistic response within each cell and within a given culture. Difficulties of attempting to relate changes in specific molecular species to subsequent whole-cell responses are discussed. Author

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Distribution Statement:

APPROVED FOR PUBLIC RELEASE