DYNAMICS OF THE CIRCULATION IN ACUTE HYPERTENSION PRODUCED BY STIMULATION OF THE CEREBRAL CORTEX.
MEDICAL COLL OF VIRGINIA RICHMOND
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Electrical stimulation of the motor cortex of the dogs brain produced an actue systemic hypertension due to marked vaso-construction, without change in cardiac output. Small increases occurred in right atrial, pulmonary atrial, and pulmonary wedge pressures. Heart rate usually remained constant. A significant correlation was found between mean aortic and pulmonary wedge pressures at the peak of the hypertension. This finding can be explained on the basis of the operation of Starlings law in the intact animal preparation used in this study. Author