RELATION OF PULMONARY VENTILATION TO ARTERIAL OXYGEN TENSION.
NAVAL SCHOOL OF AVIATION MEDICINE PENSACOLA FLA
Pagination or Media Count:
Three resting subjects breathed oxygen-nitrogen mixtures equivalent to 16,500 feet at various rates of pulmonary ventilation. The respiratory volume and arterial oxygen saturation were recorded every minute. After eight to fourteen minutes at the desired ventilatory rate, blood was withdrawn from an indwelling arterial needle, and the arterial pH, and carbon dioxide and oxygen tensions determined directly. Conclusions In resting subjects breathing 10.5 oxygen, the arterial oxygen tension bears a direct and linear relation to the respiratory minute volume, though no arterial tensions were found to exceed the tracheal oxygen tension. A moderate degree of hyperventilation during this degree of anoxia increases arterial oxygenation, and results in marked subjective improvement without recognizable symptoms of acapnia, at least during a fifteen minute period. Under these experimental conditions, the increase in arterial oxygen tension during hyperventilation is shown to be greater than the decrease in arterial carbon dioxide tension. Author