Accession Number:

AD0617980

Title:

CHARACTERISTICS OF THE ATP-ASE ACTIVITY OF ISOLATED NEURONS OF RABBIT,

Descriptive Note:

Corporate Author:

GOTEBORG UNIV (SWEDEN) INST OF NEUROBIOLOGY

Personal Author(s):

Report Date:

1964-08-31

Pagination or Media Count:

6.0

Abstract:

Isolated and homogenised DEITERS neurons from the lateral vestibular nucleus of rabbit in a Krebs-Ringer solution containing no added Mg, 1.3 micro molesml and 5 micro molesml Mg broke down ATP at the maximal rate of 0.29 0.20, 2.40 0.20, and 5.95 0.63 micro micro molescellhr. In 1.3 mM Mg solution the single cell homogenates took up phosphate at the mean rate of 2.6 0.2 micro micro molescellhr. If the rabbits were injected 1 hour before with 20 mgkg body weight of 2-amino-1-propene-1,1,3, tricarbonitrile triap, the breakdown of ATP in these latter media was 0.82 0.44, 2.5 0.60, and 6.7 1.1 micro micro molescellhr, respectively, and the quantity of inorganic phosphate liberated did not decrease. Author

Subject Categories:

Distribution Statement:

APPROVED FOR PUBLIC RELEASE