Accession Number:

AD0617454

Title:

IMMUNOCHEMICAL STUDIES ON CROSS-REACTIONS OF ANTIPNEUMOCOCCAL SERA. IV. CROSSREACTIONS OF HORSE TYPE XXII ANTIPNEUMOCOCCAL SERUM WITH DEXTRANS,

Descriptive Note:

Corporate Author:

COLUMBIA UNIV NEW YORK COLL OF PHYSICIANS AND SURGEONS

Personal Author(s):

Report Date:

1964-01-31

Pagination or Media Count:

7.0

Abstract:

A study of the cross-reactions of type XXII horse antipneumococcal serum with various dextrans has shown the presence of two populations of cross-reacting antibody molecules. The reaction of one of these with B512 dextran N236 is inhibited by the isomaltose series of oligosaccharides, isomaltohexaose and isomaltoheptaose being equal on a molar basis and the best inhibitors. On absorption of these antibodies, a second population remains which cross-reacts best with dextrans with high proportions of 1,2- and 1,3-like linkages, and for which the best inhibitors are the disaccharides kojibiose, trehalose and isomaltose the higher oligosaccharides of the isomaltose series were equal in potency to isomaltose on a molar basis. Author

Subject Categories:

Distribution Statement:

APPROVED FOR PUBLIC RELEASE