TOXICOLOGICAL EVALUATION OF AMMONIUM SULFAMATE-A HERBICIDE PREPARATION
ARMY BIOLOGICAL LABS FREDERICK MD
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Ammonium sulfamate is a comparatively weakly toxic substance. With oral administration the LD50 for mice equals 3.1g to 1 kg of body weight, for rats - 4.4gkg. There were no accumulative properties of ammonium sulfamate detected. The effects of numerous exposures to an aerosol of ammonium sulfamate in concentrations of 0.25 - 0.5 g1 caused the occurrence of desquamated catarrh of the upper respiratory tract. The application of a 20 solution of ammonium sulfamate on the skin may cause an infraction of the entirety of the surface layer of skin there is no overall toxic influence detected during this. From a hygienic point of view ammonium sulfamate may be widely used in agriculture with the application of the usual measures of protecting the respiratory organs and exposed parts of the skin.
- Agricultural Chemistry