Accession Number:

AD0612568

Title:

THE ROLE OF CEREBRAL CHOLINERGIC STRUCTURES IN LEARNING: RELATIONSHIP BETWEEN CONDITIONED RESPONSES AND THE EEG ARREST REACTION (STUDI SUL RUOLO DELLE STRUTTURE COLINERGICHE CEREBRALI NEL CONDIZIONAMENTO: RELAZIONI FRA LE RISPOSTE CONDIZIONATE E LA REAZIONE D'ARRESTO EEG),

Descriptive Note:

Corporate Author:

ROME UNIV (ITALY)

Personal Author(s):

• Ricci,Gian Franco
• Zamparo,Luisa

Report Date:

1963-01-01

Pagination or Media Count:

5.0

Abstract:

Earlier work by the authors had shown that atropine, in doses sufficient to alter the resting EEG and arrest reaction, also altered classical conditioned responses i.e., affected behavior. The current report deals with other anticholinergics, a cholinesterase, and a sympathomimetic. Scopolamine and benactyzine exerted effects similar to atropine. Eserine, when administered by itself, altered both the EEG and conditioned responses but, when administered to monkeys pretreated with an anticholinergic, it caused the EEG to return to normal and restored conditioned relfexes. Amphetamine given to monkeys pretreated with an anticholinergic did not alter the anticholinergic EEG pattern, but did restore the conditioned response. The authors propose a possible explanation for the differing effects between the cholinergic and sympathomimetic drugs. Author

Descriptors:

• *PSYCHOTROPIC AGENTS
• CONDITIONED RESPONSE
• DRUGS
• LEARNING
• BEHAVIOR
• ELECTROENCEPHALOGRAPHY
• CHOLINESTERASE
• SYMPATHOMIMETIC AGENTS
• SCOPOLAMINE
• ATROPINE
• INDOLE ALKALOIDS
• AMPHETAMINES
• MONKEYS
• ITALY

Subject Categories:

Distribution Statement:

APPROVED FOR PUBLIC RELEASE