POTENTIAL ANTIRADIATION DRUGS.
Final annual rept. for 1 Jul 63-30 Jun 64,
WYANDOTTE CHEMICALS CORP MICH
Pagination or Media Count:
N-substituted fluoroalkyl derivatives of 2-mercaptoethylamines were synthesized to serve as potential antiradiation drugs. These compounds were prepared from the thioethylation of fluoroalkylamines with ethylene sulfide. Variations in the structures of fluoroalkylamines were achieved by the development of synthetic routes towards simple fluoroalkylamines as well as fluoroalkyl-substituted aminoalcohols. A number of unsuccessful approaches towards the synthesis of 1-and 2-perfluoroalkyl-2-mercaptoethylamines were investigated. Author