RESEARCH AND DEVELOPMENT OF PROCEDURES FOR THE LOW-TEMPERATURE PRESERVATION OF BLOOD.
UNION CARBIDE CORP TONAWANDA N Y LINDE DIV
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Procedures were developed for the long term preservation of whole blood or packed red cells in the frozen state using polyvinylpyrrolidone, an extracellular polymeric solute, as the protective additive. These procedures are simple and require minimal training of an operating technician. Approximately 97 of red cells will withstand the freezing, storage and thawing process and 80 to 90 of these remain in the circulatory system 24 hours after transfusion with or without post-thaw procedures. Being useful both in emergencies and for normal usage, effort should be undertaken to achieve clinical acceptance of these blood preservation procedures. Author