Accession Number:

AD0601358

Title:

CERTAIN PECULIARITIES OF THE ADAPTATION PROCESS TO STREPTOMYCIN IN VARIOUS STRAINS OF PASTEURELLA PESTIS ON NUTRIENT MEDIA,

Descriptive Note:

Corporate Author:

ARMY BIOLOGICAL LABS FREDERICK MD

Personal Author(s):

Report Date:

1963-12-01

Pagination or Media Count:

11.0

Abstract:

Four types of Pasteurella pestis were pointed out Sensitive, weakly resistant, highly resistant dependent and highly resistant independent. The appearance and stabilization of these forms was determined by the concentration of streptomycin in the media on which the populations of strains under study were cultivated. A study of the peculiarities of dynamics of the development of streptomycin resistant strains of Pasteurella pestis during serial seedings on Hottinger agar with gradually increasing content of antibiotic, made it possible to differentiate three types of adaptation of bacterial populations to streptomycin 1 Full type Sensitive, weakly sensitive, highly resistant dependent form 2 Transitory type Sensitive, weakly resistant independent form and 3 Reduced type Sensitive, highly resistant independent form. Author

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Distribution Statement:

APPROVED FOR PUBLIC RELEASE