Accession Number:

AD0489059

Title:

A NEW SYNTHESIS FOR 6-FURFURYLAMINO-9-BETA-D-RIBOFURANOSYL PURINE (KINETIN RIBOSIDE)

Descriptive Note:

Corporate Author:

FORT DETRICK FREDERICK MD

Personal Author(s):

Report Date:

1966-08-01

Pagination or Media Count:

13.0

Abstract:

Kinetin riboside is of interest in plant physiology as a mitotic stimulant and in the tissue culture of cancer cells for its unusual differential toxicity toward adult human fibroblasts in the presence of human carcinoma cells. Three multi-step methods for its synthesis have been reported. This report describes a simple two-step synthesis for kinetin riboside that, unlike the cited methods of preparation, utilizes intermediates that are readily available and requires only a fraction as much time and effort for completion. Authentic kinetin riboside and material prepared by this synthesis were subjected to a number of physical and chemical tests and the data thus obtained are compared.

Subject Categories:

  • Organic Chemistry

Distribution Statement:

APPROVED FOR PUBLIC RELEASE