RESEARCH AND REPORTS ON EFFECTS OF ALCOHOL AND DRUGS ON RATS UNDER AMBIENT AND LOW TEMPERATURES, MEASURED BY AVOIDANCE RESPONSE.
Final research rept. 1 May 64-31 May 65,
HINE LABS INC SAN FRANCISCO CA
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This report summarizes the experimental results obtained in the evaluation of the effects of alcohol and drugs on rats under ambient and low temperatures as measured by avoidance response. Based on LD50 determinations, the toxicity of the tranquilizers, chlorpromazine and chlordiazepoxide, and the sedative hypnotics, morphine and promethazine, increased with acute exposure to cold. The toxicity of amphetamine, a stimulant, was lowered at reduced temperatures. Author
- Stress Physiology