Accession Number:

AD0477331

Title:

SODIUM TRANSPORT IN ISOLATED ILEUM FROM COBALT-60 IRRADIATED RABBITS

Descriptive Note:

Rept. for May-Sep 1964

Corporate Author:

SCHOOL OF AEROSPACE MEDICINE BROOKS AFB TX

Report Date:

1965-10-01

Pagination or Media Count:

13.0

Abstract:

The study of sodium transport in isolated ileum from 51 irradiated rabbits reveals no decrease in short-circuit current from 4 to 216 hours after exposure to 1.2 kR and from 4 to 50 hours after exposure to 2.0 kR from a Co60 source. Separate preparations of Adjacent sections of terminal ileum received simultaneous additions of either 10 mM. D-glucose or 10 mM. L-alanine to mucosa and serosa. A normal response in short-circuit current was obtained in the 1.2 kR group, and a large increase in short-circuit current response was observed in the 2.0 kR group after glucose addition. Evidence is presented that the sodium pump is not blocked after 1.2 kR and 2.0 kR doses of gamma irradiation in isolated rabbit ileum within these time intervals.

Subject Categories:

  • Radiobiology

Distribution Statement:

APPROVED FOR PUBLIC RELEASE