Accession Number:

AD0477172

Title:

PRELIMINARY STUDIES ON THE DISAPPEARANCE OF BOTULINUM TOXIN FROM THE CIRCULATING BLOOD OF RHESUS MONKEYS

Descriptive Note:

Technical memo. Oct 1964-May 1965

Corporate Author:

CHEMICAL RESEARCH AND DEVELOPMENT LABS EDGEWOOD ARSENAL MD

Report Date:

1965-12-01

Pagination or Media Count:

14.0

Abstract:

Rhesus monkeys including two survivors of previous exposures to botulinum toxin were given Type A botulinum toxin intravenously, and disappearance of the toxin from the serum was measured. These animals were given about 95 LD50s and died while there was still from 30 to 60 of the dose in the serum. Hematocrit values dropped much more swiftly and farther than did those of a control monkey bled on the same schedule.

Subject Categories:

  • Biochemistry
  • Medicine and Medical Research

Distribution Statement:

APPROVED FOR PUBLIC RELEASE