LETHAL PROCESSES IN DEHYDRATION OF MICROORGANISMS
ARMY BIOLOGICAL LABS FREDERICK MD
Pagination or Media Count:
Approaches to the study of lethal effects of dehydration and relevant experimental results obtained by the author and co-workers since 1958 are summarized informally. The paper includes 1 a working hypothesis of interacting lethal processes from which self-limiting long-term decay curves can be calculated. 2 Preliminary experimental data illustrating the types of information needed for application of the hypothesis. 3 An account of the preparation of simulated aerosols by deposition of cells upon membrane filters. 4 Approaches to the identification of lethal interactions, including the correlation of lethal effects with the colligative properties of simple additives. 5 Illustrative data for Serratia marcescens in the presence of NaC1, LiBr, and urea. 6 Data on short-term decay of washed Serratia marcescens at 13 ambient relative humidities. 7 Preliminary data on the effects of oxygen in accelerating humiditydependent decay and on possible effects of slow residual water transfer.