Accession Number:

AD0466948

Title:

DETOXIFICATION OF CROTALUS ATROX VENOM BY PHOTOOXIDATION IN THE PRESENCE OF ETHYLENE BLUE.

Descriptive Note:

Corporate Author:

ADJUTANT GENERAL'S OFFICE (ARMY) WASHINGTON DC

Personal Author(s):

• Kocholaty, W.

Report Date:

1965-05-10

Pagination or Media Count:

1.0

Abstract:

Photooxidation of crude Crotalus atrox venom by visible light in the presence of traces of methylene blue resulted in a detoxification of the venom. The detoxified venom when injected in the rabbits gave rise to antibodies which protected mice against the action of the native venom. Various changes occurring during photooxidation in the properties of the venom are described. Author

Descriptors:

• *PHOTOCHEMICAL REACTIONS
• PHOTOSENSITIVITY(BIOLOGICAL)
• VENOMS
• BIOCHEMISTRY
• IMMUNITY
• OXIDATION
• ANTIGENS
• ANTIBODIES
• BIOLOGICAL STAINS
• TOXICITY
• REPTILES
• ENZYMES
• PH FACTOR

Subject Categories:

Distribution Statement:

APPROVED FOR PUBLIC RELEASE