Accession Number:

AD0453491

Title:

DELAYED EFFECTS OF RADIATION ON THE HUMAN CENTRAL NERVOUS SYSTEM. EARLY AND LATE DELAYED REACTIONS,

Descriptive Note:

Corporate Author:

TELE-DYNAMICS DIV AMERICAN BOSCH ARMA CORP PHILADELPHIA PA

Personal Author(s):

Report Date:

1964-01-01

Pagination or Media Count:

7.0

Abstract:

Two cases of delayed effects of radiation on the central nervous system of man are reported. One demonstrates the rare early delayed reaction which occurs approximately three months after radiation. The lesions resemble most closely the plaques of acute multiple sclerosis and are not associated with degenerative vascular changes. This patient probably represents an extreme of the early delayed reaction reported by Scholz in dogs. There is clinical evidence suggesting that some degree of damage of this type occurs more frequently than has been suspected. The other patient had the late delayed reaction in which there are marked degenerative vascular alternations and severe destruction of the white matter with little cortical involvement. This patient is an extreme example of the well-documented late delayed effects of radiation and is presented for contrast with the patient in case 1. The presence of hypertrophic neurons in the irradiated cortex is a new and unexplained finding. Author

Subject Categories:

Distribution Statement:

APPROVED FOR PUBLIC RELEASE