Accession Number:

AD0441231

Title:

DETERMINATION OF HYDRAZINE AND 1-METHYLHYDRAZINE IN BLOOD SERUM.

Descriptive Note:

Rept. for Jun 62-Aug 63,

Corporate Author:

AIR FORCE AEROSPACE MEDICAL RESEARCH LAB WRIGHT-PATTERSON AFB OH

Personal Author(s):

• Reynolds, Barbara A.
• Thomas, Anthony A.

Report Date:

1964-04-01

Pagination or Media Count:

11.0

Abstract:

A simple procedure is described for measuring microgram amounts of hydrazine in the blood serum of rats. The procedure, with a minor modification, can be used for measuring microgram amounts of 1-methylhydrazine. The report presents calibration ranges of 0.5-5.0 microgramsml and 0.5-10.0 microgramsml of hydrazine and 1-methylhydrazine, respectively. Data are presented on the dose-blood-level relationship of hydrazine and 1-methylhydrazine in rats following intraperitoneal injection. Minimum detectable dose levels were 0.6 mgkg and 3.0 mgkg of hydrazine and 1-methylhydrazine, respectively. Author

Descriptors:

• *BLOOD SERUM
• *BLOOD CHEMISTRY
• CHEMISTRY
• METHYL HYDRAZINES
• MEASUREMENT
• RATS
• CHEMICAL ANALYSIS

Subject Categories:

Distribution Statement:

APPROVED FOR PUBLIC RELEASE