DETERMINATION OF HYDRAZINE AND 1-METHYLHYDRAZINE IN BLOOD SERUM.
Rept. for Jun 62-Aug 63,
AIR FORCE AEROSPACE MEDICAL RESEARCH LAB WRIGHT-PATTERSON AFB OH
Pagination or Media Count:
A simple procedure is described for measuring microgram amounts of hydrazine in the blood serum of rats. The procedure, with a minor modification, can be used for measuring microgram amounts of 1-methylhydrazine. The report presents calibration ranges of 0.5-5.0 microgramsml and 0.5-10.0 microgramsml of hydrazine and 1-methylhydrazine, respectively. Data are presented on the dose-blood-level relationship of hydrazine and 1-methylhydrazine in rats following intraperitoneal injection. Minimum detectable dose levels were 0.6 mgkg and 3.0 mgkg of hydrazine and 1-methylhydrazine, respectively. Author