EFFECT OF ACCLIMATIZATION TO 2 C ON HOST SUSCEPTIBILITY TO KLEBSIELLA PNEUMONIAE CHALLENGE
UTAH UNIV SALT LAKE CITY SALT LAKE CITY United States
Pagination or Media Count:
Adult albino mice were exposed to 2 C in groups for varying time periods prior to challenge intraperitoneally with l LD50 of Klebsiella pneumoniae. Animals exposed to the low temperature for up to five days prior to challenge showed no significant differences in mortality from the controls. Statistically significant survival ratios were obtained if the mice were exposed to cold for more than five days prior to challenge. No deaths were observed in comparable specifically immunized groups of animals.