Accession Number:

AD0429507

Title:

THYROIDAL INFLUENCE ON ALTITUDE TOLERANCE,

Descriptive Note:

Corporate Author:

JEFFERSON MEDICAL COLL PHILADELPHIA PA

Personal Author(s):

Report Date:

1963-12-01

Pagination or Media Count:

3.0

Abstract:

Ths investigation aimed at obtaining support for the concept that lesser amounts of cortisol are effective in prolonging the survival time of thyroidectomized rats exposed to altitude because of a decreased catabolism of the steroid in hypothyroid animals. The data indicate that hyperthyroid animals are more susceptible to altitude exposure than are normal animals, and a greater amount of cortisol is required to protect altitude-exposed adrenalectomized animals that have also been thyroidectomized. Increased thyroid function in altitude-exposed animals is indicated by measurements on the following parameters which were increased thyroidal uptake of I131, release of thyroidal I131, erythrocyte uptake of I131-labeled triiodothyronine. Author

Subject Categories:

Distribution Statement:

APPROVED FOR PUBLIC RELEASE