Accession Number:

AD0429378

Title:

NEW METHODS DEVELOPMENT FOR IRRITANT SCREENING

Descriptive Note:

Quarterly progress rept. no. 3, 23 Sep-22 Dec 1963

Corporate Author:

BIONETICS RESEARCH LABS INC FALLS CHURCH VA

Personal Author(s):

Report Date:

1964-01-10

Pagination or Media Count:

13.0

Abstract:

Peritoneal mast cells have been found to liberate too small a quantity of histamine to permit evaluation of the activity of irritants. Guinea pig lungs appear suitable. Mice and dogs appear inferior to rabbits for evaluation of eye irritation. Assessment by current methods has now been accomplished on a cumulative total of approximately 280 compounds.

Subject Categories:

  • Chemical, Biological and Radiological Warfare
  • Medicine and Medical Research

Distribution Statement:

APPROVED FOR PUBLIC RELEASE