DOUBLE ISOTOPE DERIVATIVE MEASUREMENT OF HORMONES IN STRESS.
Final technical rept., 1 July 62-30 June 63,
WALTER REED ARMY INST OF RESEARCH WASHINGTON D C
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The double isotope derivative measurement of hormones in stress has been applied to the measurement of aldosterone in urine and plasma samples from the rhesus monkey. The data show that definite patterns of response in aldosterone secretion is associated with selected stress situations. The direction and magnitude of these responses is discussed and data is given relative to some of the parameters which influence these responses. The application of the double isotope derivative measurement of plasma testosterone is examined. Redesign and evaluation of the analytical method is discussed and some preliminary results are reported. Author