THE STUDY OF SPONTANEOUS POTENTIALS FROM EXPLANTS OF BRAIN TISSUE IN VITRO.
TEXAS UNIV GALVESTON MEDICAL BRANCH
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Spontaneous potentials from explants of brain tissue in virto were explored. The principal divisions of activity were recorded from cerebellum of chick, rat and human telencephalon, pons, thalamus, corpus striatum, medulla oblongata, optic lobes, and spinal cord. The effects of major changes in the gaserous environment, in temperature and of some of the common drugs known to have an effect on the CNS were observed and recorded. The results of these were found to be reversible and to resemble closely those observed as a result of the action of the same agents on the intact CNS. They were interpreted to show that the electrical disturbances being recorded were the products of a genuine physiological phenomenon arising from cells which were a vital part of the functional apparatus of the CNS. Author