Accession Number:

AD0421113

Title:

CARDIOVASCULAR RESPONSE TO STRESS IN SURGICAL PATIENTS UNDER HALOTHANE ANESTHESIA,

Descriptive Note:

Corporate Author:

WASHINGTON UNIV SEATTLE SCHOOL OF MEDICINE

Personal Author(s):

Report Date:

1943-01-01

Pagination or Media Count:

20.0

Abstract:

Fifteen unselected patients scheduled for elective surgery were monitored for cardiac-output, total blood volume, blood PaO2, PaCO2, and apH, E.C.G. and continuous arterial and venous pressures before induction of halothane-O2 anesthesia, after induction of anesthesia but before surgery, and following surgery and anesthesia. The average mean arterial pressure was decreased significantly during anesthesia and postoperatively. The cardiac rate was significantly changed only in the postoperative period due to the stress caused by surgery and blood loss. Cardiac -output and stroke volume were decreased with deep anesthesia and in the postoperative period, again due to stress of surgery and blood loss. In general, there was a tendency toward CO2 retention and acidosis in all patients, but this was not of a significant degree. Light halothane anesthesia did not depress cardiovascular function to a significant degree, but did cause very mild respiratory depression. The basis of this lack of cardiovascular depression is discussed. Depression occurring with increased duration of anesthesia is also discussed. Author

Subject Categories:

Distribution Statement:

APPROVED FOR PUBLIC RELEASE