EXPERIMENTAL STUDY OF ACUTE AND CHRONIC INJURY TO RENAL TUBULES
Annual progress rept. 1 Dec 1962-30 June 1963
JOHNS HOPKINS UNIV BALTIMORE MD DEPT OF PATHOLOGY
Pagination or Media Count:
A study of the normal ultrastructure of the rat kidney was undertaken as a basis for a study of the serial morphologic changes in acute tubular necrosis. By electron microscopy, a close structural relationship between endoplasmic reticulum and cytosomes and between cytosomes and the Golgi region was established. The tytosomes involved are acid-phosphatase containing and may be regarded, preliminarily, as lysosomes. The technique of nephron-dissection has been perfected in the laboratory and is being applied to normal kidney tissues.
- Medicine and Medical Research