Accession Number:

AD0405883

Title:

EXPERIMENTAL STUDY OF ACUTE AND CHRONIC INJURY TO RENAL TUBULES

Descriptive Note:

Annual progress rept. 1 Dec 1962-30 June 1963

Corporate Author:

JOHNS HOPKINS UNIV BALTIMORE MD DEPT OF PATHOLOGY

Personal Author(s):

Report Date:

1963-06-30

Pagination or Media Count:

8.0

Abstract:

A study of the normal ultrastructure of the rat kidney was undertaken as a basis for a study of the serial morphologic changes in acute tubular necrosis. By electron microscopy, a close structural relationship between endoplasmic reticulum and cytosomes and between cytosomes and the Golgi region was established. The tytosomes involved are acid-phosphatase containing and may be regarded, preliminarily, as lysosomes. The technique of nephron-dissection has been perfected in the laboratory and is being applied to normal kidney tissues.

Subject Categories:

  • Medicine and Medical Research

Distribution Statement:

APPROVED FOR PUBLIC RELEASE