Accession Number:

AD0405017

Title:

A COMPARATIVE STUDY OF THE INTRANASAL AND AEROSOL METHODS OF VACCINATION AGAINST INFLUENZA

Descriptive Note:

Corporate Author:

ARMY BIOLOGICAL LABS FREDERICK MD

Personal Author(s):

Report Date:

1963-04-01

Pagination or Media Count:

10.0

Abstract:

The reactogenicity of influenza vaccines during the aerosol method of immunization was lower than during the intranasal method. Along with this there were no temperature reactions over 37.5 noted. Other symptoms of vaccinal reaction head cold, headache, sneezing and others were ob served less seldom during the aerosol method and were not so sharply expressed. The egg tissue and egg-tissue combined type A2 vaccine provided the best indices of adaptability and immunologi cal effectiveness. Comparative data testifies to the future prospects and convenience of the aerosol method for the immunization of large masses of the population with live influenza vac cine, however for a conclusive evaluation of it, further investigations are required.

Subject Categories:

  • Pharmacology

Distribution Statement:

APPROVED FOR PUBLIC RELEASE