Accession Number:

AD0402580

Title:

CORTICOSTEROIDS IN HUMAN PAROTID FLUID FOLLOWING ORAL HYDROCORTISONE DOSAGE,

Descriptive Note:

Corporate Author:

SCHOOL OF AEROSPACE MEDICINE BROOKS AFB TEX

Personal Author(s):

Report Date:

1963-04-01

Pagination or Media Count:

3.0

Abstract:

A single 20-minute parotid fluid sample was collected prior to, and six 20-minute samples were collected subsequent to the oral administra tion of 50-milligrams of hydrocortisone to 30 healthy young adult males. Blood was drawn be fore dosage and 2 hours thereafter. The follow ing conclusions were drawn The serum free 17 OHCS increase after dosage was highly significant. Hydrocortisone did not exert a significant effect on parotid fluid flow rate. A highly significant increase in parotid fluid free 17-OHCS levels was found in the 40- to 60-minute sample. A significant response was elicited in all subjects within 2 hours. Author

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Distribution Statement:

APPROVED FOR PUBLIC RELEASE