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THE POST COLD BEHAVIOR OF RIBOFLAVIN DEFICIENT RATS
ARCTIC AEROMEDICAL LAB FORT WAINWRIGHT ALASKA
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The post-cold behavior of riboflavin-deficient rats was studied. It was observed that rats depleted at 5 C for four weeks resumed slow growth due to fat and water deposition upon return to 25 C. Gross symptoms of the deficiency did not appear as soon in the post-cold rats as in the warm rats. Total riboflavin losses from the liver were rapid initially, leveling out at about one-third of normal concentration, but there was little difference between groups. Liver and kidney xanthine oxidase activity did not fall as rapidly as did riboflavin, and the post-cold rats appear to maintain higher levels throughout the experiment. Author
APPROVED FOR PUBLIC RELEASE