Accession Number:

AD0293173

Title:

STUDIES ON THE METABOLISM OF FATTY ACIDS AND RELATED SUBSTANCES IN ANIMALS EXPOSED TO COLD

Descriptive Note:

Corporate Author:

TUFTS UNIV BOSTON MASS SCHOOL OF MEDICINE

Personal Author(s):

Report Date:

1956-12-01

Pagination or Media Count:

1.0

Abstract:

The development or perfection of techniques in the study of metabolism of fatty acids and related substances in animals exposed to cold was investigated. The experiments were all performed on liver slices from male Wistar rats, 3 12 to 6 months old, fed on a standard synthetic diet. Control animals were kept at 25 C. warm rats the experimental group was exposed to 0-2 C. cold rats. The food intake of the cold rats was about 1 12 times that of the warm rats, while the water intake of the latter was 1 12 times that of the former. During a 10-day experimental period the warm rats gained about 7 in body weight, while the cold rats lost about 6 in the same period. The water content of the whole animal was studied in two warm and two cold rats, and no appreciable difference was found. Certain of the cold rats died with characteristic bodily changes. Author

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Distribution Statement:

APPROVED FOR PUBLIC RELEASE