Accession Number:

AD0292926

Title:

THE METABOLISM OF SIMPLE COMPOUNDS IN MICRO-ORGANISMS

Descriptive Note:

Corporate Author:

LEICESTER UNIV (ENGLAND)

Personal Author(s):

Report Date:

1962-09-20

Pagination or Media Count:

1.0

Abstract:

Results obtained indicate that 1 the formation of isocitrate lyase when E. coli grow on acetate is a consequence of de novo protein synthesis 2 acetate per se is not an inducer of isocitrate lyase formation but acts in an indirect manner, probably by relieving enzyme repression 3 growth of Rps. spheroides on acetate, aerobically in the dark or anaerobically in the light, does not involve the glyoxylate cycle 4 anaerobic growth of an organism, tentatively identified as Cl. kluyveri, on ethanol plus acetate also does not involve the glyoxylate cycle 5 inducible amidase formation by Ps. aeruginosa growing on acetamide is discontinuous and either the nature of the enzyme formed or its mode of formation is influenced by the nature of the inducing agent 6 growth of M. denitrificans on glycollate involves a new route in which betahydroxyaspartate may be an intermediate and 7 growth of Pseudomonas sp. on itaconate necessitates its prior activation to itaconyl coenzyme A, which is transformed to pyruvate and acetyl coenzyme A, probably via citramalyl coenzyme A. Author

Subject Categories:

Distribution Statement:

APPROVED FOR PUBLIC RELEASE