THE DUAL NATURE OF RESISTANCE MECHANISMS AS REVEALED BY STUDIES OF ANTHRAX SEPTICEMIA
ARMY BIOLOGICAL LABS FREDERICK MD
Pagination or Media Count:
From studies of septicemic anthrax, resistance is described in relation to toxin and to growth of bacilli. this description is based on the observations that the terminal concentrations of bacilli in the blood are influenced primarily by the susceptibility of the host to toxin, whereas the death response time of the host is dependent on both resistance to bacilli and toxin susceptibility. resistance to the establishment and growth of infecting organisms and susceptibility to the toxin produced by growth of the bacilli are separate aspects of pathogenesis. a complete description of pathogenesis must treat accordingly both these phenomena as individual entities.