Accession Number:

AD0289618

Title:

THE ABSORPTION OF FATTY ACIDS BY INTESTINAL PERFUSION IN SITU

Descriptive Note:

Corporate Author:

ARMY BIOLOGICAL LABS FREDERICK MD

Personal Author(s):

Report Date:

1962-03-15

Pagination or Media Count:

1.0

Abstract:

The absorption of lipids by the gastrointestinal tract has been studied by the classical techniques of fat balance studies, the Cori technique, thoracic duct cannulated animals, and histological sections. The in vitro techniques with inverted intestinal sacs and perfusion of isolated intestinal segments have been utilized recently. Some of the limitations and objections to both the previously employed in vitro and in vivo techniques can be overcome by the use of the in situ perfusion technique described by Jacobs and Luper for the study of carbohydrate absorption. Pivalic acid-1-C14 as a model substrate has been shown to be well absorbed by this technique. Preliminary studies in progress indicate absorption of a high molecular weight fatty acid palmitic. Author

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Distribution Statement:

APPROVED FOR PUBLIC RELEASE