Accession Number:

AD0287075

Title:

ADDITIVE EFFECTS OF ACETAZOLAMIDE AND FAT EMULSION ON THE A-A B(CO2) DIFFERENCE

Descriptive Note:

Corporate Author:

SCHOOL OF AEROSPACE MEDICINE BROOKS AFB TEX

Personal Author(s):

Report Date:

1962-04-01

Pagination or Media Count:

1.0

Abstract:

Alveolar and arterial gas tensions P were measured in anesthetized dogs during a control period, after intravenous injections of a carbonic anhydrase inhibitor, and after rapid intravenous infusion of fat emulsion. The alveolararterial A-a PCO2 difference increased from about 6 mm. Hg during the control period to 26 mm. Hg after carbonic anhydrase inhibition. A further increase took place after fat emulsion when the A-a PCO2 difference averaged 35 mm. Hg. There was no increase in the A-a PO2 difference between carbonic anhydrase inhibition and fat emulsion. The additive increase in the A-a PCO2 difference strongly suggested that fat emulsion did not further interfere with the interconversion of CO2 and bicarbonate. Author

Subject Categories:

Distribution Statement:

APPROVED FOR PUBLIC RELEASE