Accession Number:
AD0287075
Title:
ADDITIVE EFFECTS OF ACETAZOLAMIDE AND FAT EMULSION ON THE A-A B(CO2) DIFFERENCE
Descriptive Note:
Corporate Author:
SCHOOL OF AEROSPACE MEDICINE BROOKS AFB TEX
Personal Author(s):
Report Date:
1962-04-01
Pagination or Media Count:
1.0
Abstract:
Alveolar and arterial gas tensions P were measured in anesthetized dogs during a control period, after intravenous injections of a carbonic anhydrase inhibitor, and after rapid intravenous infusion of fat emulsion. The alveolararterial A-a PCO2 difference increased from about 6 mm. Hg during the control period to 26 mm. Hg after carbonic anhydrase inhibition. A further increase took place after fat emulsion when the A-a PCO2 difference averaged 35 mm. Hg. There was no increase in the A-a PO2 difference between carbonic anhydrase inhibition and fat emulsion. The additive increase in the A-a PCO2 difference strongly suggested that fat emulsion did not further interfere with the interconversion of CO2 and bicarbonate. Author