EFFECTS OF DEPLETION OF SOME PHYSIOLOGICAL SUBSTANCES ON THE DEVELOPMENT OF ACUTE RADIATION SICKNESS
Annual progress rept. 1 Sep 1961-1 Sep 1962
CALIFORNIA UNIV SAN FRANCISCO MEDICAL CENTER
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A preliminary study has been made of the effects of whole body exposure to penetrating ionizing radiation X-rays, 400 rads on blood end tissue levels of ascorbic, dehydro-ascorbic and diketo-gulonic acid. This was undertaken to test the hypothesis that the rapid oxidation of ascorbic acid to its dehydro-ascorbic form may be responsible for radiobiological damage.