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COLD INJURY AT THE CELLULAR LEVEL
ARCTIC AEROMEDICAL LAB FORT WAINWRIGHT ALASKA
Pagination or Media Count:
The effects of hypothermia on the tissues and cells were investigated. Hypothermia causes a significant increase in the metabolic rate of liver slices it significantly depresses the metabolic rate of kidney cortex slices. There is strong evidence to suggest that the enzyme system responsible for moving pyruvate into the TCA cycle is potentiated. Increases in wet-dry ratios were seen in liver, kidney, and heart however, they tended to be transitory. It is suggested that the ether-extractable lipid may be affected by hypothermia this, however, was not statistically significant. Evidence of CNS damage was also noted it may be a strain difference. Author
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