Accession Number:

AD0271593

Title:

HISTOPATHOLOGICAL STUDIES OF TISSUE REACTIONS TO VARIOUS METALS IMPLANTED IN CAT BRAINS

Descriptive Note:

Corporate Author:

AERONAUTICAL SYSTEMS DIV WRIGHT-PATTERSON AFB OHIO AEROSPACE MEDICAL DIV

Report Date:

1961-10-01

Pagination or Media Count:

1.0

Abstract:

Metal rods of gold, platinum, silver, stainless steel, tantalum, and tungsten were implanted in cat brain tissue. The resulting changes were observed for as long as 6 months. The stainless steel and gold rods caused the least reaction while platinum and tantalum caused a slightly greater response. The lesions resulting from tungsten were comparatively more extensive. Silver elicited a violent tissue response with the astrocytic reaction extending to 3.75 mm in diameter in a lesion produced by a 7-day implantation. This evidence indicates a preference of metals to be used in the fabrication of intracerebral electrodes from the standpoint of tissue reaction. Author

Subject Categories:

Distribution Statement:

APPROVED FOR PUBLIC RELEASE