Accession Number:

AD0270485

Title:

CHLOROTHIAZIDE ATTENUATION OF THE PRESSOR RESPONSES TO EPINEPHRINE, LEVARTERENOL, AND ANGIOTENSIN IN THE PERFUSED RENAL VASCULAR BED

Descriptive Note:

Corporate Author:

ARMY MEDICAL RESEARCH LAB FORT KNOX KY

Report Date:

1961-11-10

Pagination or Media Count:

10.0

Abstract:

A study was made to investigate the effect of acute local chlorothiazide administration on renal vascular resistance and to ascertain if chlorothiazide alters the pressor response to vasoactive agents. Chlorothiazide did not ACUTELY ALTER RENAL VASCULAR RESISTANCE. The pressor responses to epinephrine, levarterenol, and angiotensin were attenuated and the depressor response to magnesium chloride MgCl2 was potentiated. Acute local administration of chlorothiazide in the perfused renal vascular bed of the dog acutely alters the pressor response to certain vasoactive agents. Author

Subject Categories:

Distribution Statement:

APPROVED FOR PUBLIC RELEASE