Accession Number:

AD0266589

Title:

LATE TESTICULAR LESIONS IN IRRADIATED MONKEYS (MACACA MULATTA)

Descriptive Note:

Corporate Author:

SCHOOL OF AEROSPACE MEDICINE BROOKS AFB TEX

Personal Author(s):

Report Date:

1961-06-01

Pagination or Media Count:

1.0

Abstract:

Prepubertal Macaca mulatta monkeys were exposed to acute and fractionated doses of gamma or neutron radiation or to both. Testicular tissues were examined 3 to 8 years later for the presence and severity of permanent lesions. The Macaca mulatta monkey is more sensitive to the permanently damaging effects of ionizing radiation than are the common small laboratory animals and may be comparable to man. Lesions were demonstrated in animals exposed to as little as 154 rep of gamma radiation and a threshold of 57 rep was estimated. The relative biologic effectiveness for neutrons could not be determined, but it is probably less than 2. The degree of testicular damage is relatively independent of dose rate and fractionation but is dependent primarily on the cumulative dose administered. Author

Subject Categories:

Distribution Statement:

APPROVED FOR PUBLIC RELEASE