Accession Number:

AD0263342

Title:

DESIGN, DEVELOP AND STUDY GERMFREE ISOLATORS FOR USE WITH PATIENTS AND RESEARCH

Descriptive Note:

Corporate Author:

NOTRE DAME UNIV IND LOBUND INST

Personal Author(s):

Report Date:

1961-08-31

Pagination or Media Count:

1.0

Abstract:

A series of flexible film isolators have been designed, built and tested on major surgical procedures with large animals. Over 300 pigs and several goats, lambs, dogs and a burro have been delivered germfree in these isolators. A search is being made to find the microbes in the intestinal tract that are responsible for many of the differences between germfree and conventional animals. Clostridium difficile was found to be the only organism among 60 tested that would produce a normal sized cecum in pure culture. Author

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Distribution Statement:

APPROVED FOR PUBLIC RELEASE