INVESTIGATIONS OF THE METHODS FOR SEPARATING BIOLOGICALLY AND MEDICALLY IMPORTANT SUBSTANCES OF LARGE MOLECULAR WEIGHT
Final Technical rept. no. 3, 1 June 1960-31 May 1961
UPPSALA UNIV (SWEDEN)
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Although the main part of the research work has been directed towards the development and improvement of separation methods, this has been done with much attention to possible applications and many such examples are reported for example, new possibilities of virus purification, separation of bacteria and other microbiological materials, etc. Some procedures which originally were introduced chiefly for particle separation have been extended also to smaller molecules, whereas other procedures which have their main application in the low molecular-weight field have now been modified to be useful also with large molecules and particles. In both cases a surprisingly high degree of specificity has often been observed. It is believed that the new methods for the separation of biological particles, being both highly specific and comparatively gentle non-destructive will prove of value not only for preparative purposes but also as an approach to the study of the micro-structure of biological materials of all kinds.