Accession Number:

AD0258341

Title:

STUDY OF SPREADING OF SOLUTIONS ON CUTANEOUS SURFACES AND PENETRATION INTO SKIN

Descriptive Note:

Comprehensive rept.

Corporate Author:

MASSACHUSETTS GENERAL HOSPITAL BOSTON

Personal Author(s):

Report Date:

1961-06-12

Pagination or Media Count:

20.0

Abstract:

Four mechanisms which may be active in preventing the penetration of ionic surfactants through excised human skin are 1 physical and chemical structures and reactions which make difficult the establishment of a continuous aqueous pathway through the skin, 2 steric hindrance, 3 electrostatic repulsion, and 4 combination of surfactants with proteins in the stratum corneum. Author

Subject Categories:

Distribution Statement:

APPROVED FOR PUBLIC RELEASE