Accession Number:

AD0253096

Title:

METABOLISM OF CORTISOL BY SUBCELLULAR FRACTIONS OF THE RAT LIVER

Descriptive Note:

Corporate Author:

ARMY MEDICAL RESEARCH LAB FORT KNOX KY

Personal Author(s):

Report Date:

1961-03-02

Pagination or Media Count:

14.0

Abstract:

The metabolism of cortisol by the subcellular fractions of the rat liver was investigated in order to determine the intracellular distribution of enzymes responsible for the formation of various cortisol metabolites. With and without addition of a TPNH-regenerating system differences were observed in the metabolism of cortisol by the nuclei, mitochondria, microsomes and supernatant fractions of the rat liver. Six metabolites were isolated and identified. Author

Subject Categories:

Distribution Statement:

APPROVED FOR PUBLIC RELEASE