Accession Number:

AD0248883

Title:

ELECTROPHORETIC MOBILITY AND ANTIGENICITY OF X-IRRADIATED HUMAN SERUM GAMMA GLOBULIN

Descriptive Note:

Corporate Author:

ARMY MEDICAL RESEARCH LAB FORT KNOX KY

Personal Author(s):

Report Date:

1960-12-14

Pagination or Media Count:

16.0

Abstract:

EXPOSURE OF HSGG TO VARIOUS DOSES OF X-RAYS RESULTS IN THE PRODUCTION OF MOLECULES ELECTROPHORETICALLY DISTINCT FROM THE PARENT PROTEIN. THE EVIDENCE THAT STRUCTURAL CHANGES TAKE PLACE IS GIVEN SUPPORT BY THE FINDING THAT THE ANTIGENIC SPECIFICITY OF THE NEW DERIVATIVE IS FAR REMOVED FROM THAT OF THE STARTING MATERIAL. IT IS SUGGESTED THAT HSGG DENATURED BY IONIZING RAYS HAS DEFINITE AND CONTROLLABLE CHARACTERISTICS

Subject Categories:

  • Pharmacology

Distribution Statement:

APPROVED FOR PUBLIC RELEASE