Accession Number:

AD0163755

Title:

Alpha Adrenergic Blocking Agents.

Descriptive Note:

Patent,

Corporate Author:

OFFICE OF THE SECRETARY OF THE ARMY WASHINGTON D C

Personal Author(s):

Report Date:

1971-12-21

Pagination or Media Count:

3.0

Abstract:

The patent describes the pharmacological use of compounds having the following formula H2NCH2mNHCH2nSY wherein m may be the integers 4 through 10 and n, 2 through 10, and SY is a sulfur containing function which may be metabolically converted to an --SH group, such as salts of thiols, phosphorothioic acid, thiosulfuric acid, alkyl thioethers, aryl thioethers, aralkyl thioethers and heteryl thioethers. The compounds of this invention are useful agents in blocking alpha-adrenergic mediated responses in animals and in management of conditions such as hemorrhagic hypotensions, pheochromocytoma, and Raynauds disease.

Subject Categories:

  • Pharmacology

Distribution Statement:

APPROVED FOR PUBLIC RELEASE