Accession Number:

AD0006423

Title:

ANTIGENIC STUDIES ON INFLUENZA VIRUS

Descriptive Note:

Semi-annual progress rept.

Corporate Author:

JOHNS HOPKINS UNIV BALTIMORE MD

Personal Author(s):

• Ward, Thomas G.

Report Date:

1953-01-01

Pagination or Media Count:

5.0

Abstract:

A study was made of relationships between tissue culture and influenza virus with radioactive phosphorus as the indicator system. Lee, PR8, and Thompson influenza virus strains were absorbed and eluted from normal chicken red blood cells rbcs. When a constant amount of inorganic radioactive phosphorus was added to the rbcs, the virus-treated cells acquired more phosphorus than cells treated with normal allantoic fluid. The yolks of 7-day- old chick embryos were inoculated with radioactive phosphorus. The embryos were then reincubated for 5 days, after which the rbcs were removed. Treatment of the rbcs with virus and with normal allantoic fluid resulted in no difference with respect to the release of phosphorus from the surface of the cell.

Descriptors:

• *TISSUE CULTURE
• *CHEMICAL INDICATORS
• *INFLUENZA VIRUS
• RADIOACTIVITY
• EMBRYOS
• PHOSPHORUS
• INORGANIC MATERIALS
• RELEASE
• STRAINS(BIOLOGY)
• SURFACES
• CELLS(BIOLOGY)

Subject Categories:

• Microbiology
• Pharmacology

Distribution Statement:

APPROVED FOR PUBLIC RELEASE